Oct 19, 2012
Cape Town lab commissions cyclotron to manufacture FDGBack
Cape Town|Construction|Engineering|SECURITY|Africa|IThemba LABS|NTP Radioisotopes|Nuclear|Nuclear Energy Corporation|Security|Siemens|Africa|South Africa|Panorama Medical Centre|Security|Tygerberg Facility|Tygerberg Hospital|Energy|Equipment|Maintenance|Nuclear|Product|Security|Cancer|Cancers|Disease|Radiation Treatment|Eastern Cape|Western Cape|Annare Ellmann|Clive Naidoo|Infrastructure|Security|Eastern Cape|Radiation|Radiopharmaceuticals|Tomography
© Reuse this
The cyclotron was installed and commissioned at iThemba LABS’ Faure site just outside of Cape Town during September and would be used to manufacture the radiopharmaceutical 18F Fluorodeoxyglucose (FDG), the first FDG product already having been produced on September 26.
FDG is the most common radiopharmaceutical used to carry out positron emission tomography (PET) scanning, a technique which is used in the diagnosis of a number of cancers and allows for treatment guidance and management of the disease.
NTP Radioisotopes is a subsidiary of the Nuclear Energy Corporation of South Africa and has its main production facility at Pelindaba, in the North West province. It is the key South African supplier of FDG.
However, as FDG has a half-life of just under 110 minutes, NTP Radioistotopes has had a six-year collaboration with iThemba Labs to produce the radiopharmaceutical to supply local PET facilities in the Western and Eastern Cape.
Earlier in 2012, the opening of a new positron emission tomography/computed tomography (PET/CT) centre situated at Tygerberg Hospital increased demand on FDG production at iThemba LABS, which has prompted the acquisition of the new Siemens 11 MeV cyclotron to ensure better security of supply.
While NTP Radioisotopes purchased the cyclotron at a cost of approximately R10-million, iThemba LABS provided the R2-million that was required to construct the infrastructure to house the cyclotron, as while the new cyclotron is self-shielding, the construction of a vault-like facility with reinforced flooring was still required.
Both stakeholders hoped the new facility would be able to meet the demand for FDG in the Western Cape for the next 15 to 20 years. At present there were only two cancer diagnostic infrastructure centres in the Western Cape requiring FDG, these being the Tygerberg facility and the Cape PET/CT Centre situated in the Panorama Medical Centre.
The new cyclotron would allow for the production of the FDG five days a week and would consequently reduce the demand on the main 200 MeV accelerator at iThemba LABS which had up until September been producing the FDG supply for the region. At present the 200 MeV cyclotron’s time is divided equally between radioisotope production, physics research and medical radiation treatment.
Dr Annare Ellmann, executive head of nuclear medicine at Tygerberg Hospital was excited about the facility. “The benefits that this brings to our patients one cannot really express, they are so multiple. On the one side for the regular oncology patients, our regular other chemical patients . . . but also specifically in the academic sector the value that we can add to research,” she said.
Speaking to Engineering News Online, iThemba LABS head of radionuclide production Dr Clive Naidoo, said the 11 MeV cyclotron would also have the capacity to support the production of other 18F radiopharmaceuticals such as 18F-DOPA and 18F-fallypride for use in medical diagnosis.
The operation of the equipment will be undertaken by Naidoo’s existing staff complement and no additional personnel have been required. According to Naidoo, the equipment is on the whole easier to maintain than iThemba LABS larger cyclotrone with maintenance periods of only two weeks required every six months, which is significantly less than that required by the 200 MeV facility which can add up to a few months each year, he said.
Edited by: Creamer Media Reporter© Reuse this Comment Guidelines (150 word limit)
Updated 6 hours ago South Africa’s National Treasury on Friday reissued its amended request for proposal (RFP) for the five-year multibillion-rand project to replace the legacy systems currently in use with an enterprise resource planning (ERP) solution for an integrated financial...
Updated 6 hours ago The handover of specialised computer equipment to the Umfolozi Technical and Vocational Education and Training College would address one of the greatest challenges faced by Transnet Port Terminals (TPT) at the Port of Richards Bay – a lack of skills in a highly...
Updated 7 hours ago Through hosting the WorldSkills 2014 competition’s mechatronic pre-national finals, industrial control and automation company Festo would promote and support skills development. Festo said the mechatronic competition would give schoolchildren, trainees and students...
Recent Research Reports
Defence 2014: A review of South Africa's defence industry (PDF Report)
Creamer Media’s Defence 2014 report examines South Africa’s defence industry, with particular focus on the key participants in the sector, the innovations that have come out of the sector, local and export demand, South Africa’s controversial multibillion-rand...
Road and Rail 2014: A review of South Africa's road and rail infrastructure (PDF report)
Creamer Media’s Road and Rail 2014 report examines South Africa’s road and rail transport system, with particular focus on the size and state of the country’s road and rail network, the funding and maintenance of these respective networks, and the push to move road...
Real Economy Year Book 2014 (PDF Report)
This edition drills down into the performance and outlook for a variety of sectors, including automotive, construction, electricity, transport, steel, water, coal, gold, iron-ore and platinum.
Real Economy Insight: Automotive 2014 (PDF Report)
This four-page brief covers key developments in the automotive industry over the past 12 months, including an overview of South Africa’s automotive market, trade figures, production and the policies influencing the sector.
Real Economy Insight: Construction 2014 (PDF Report)
This five-page brief covers key developments in the construction industry over the past 12 months. It provides an overview of the sector and includes details of employment in the sector, infrastructure and municipal spending, as well as insight into companies’...
Real Economy Insight: Electricity 2014 (PDF Report)
This five-page brief covers key developments in the electricity industry over the past 12 months, including details of State-owned power utility Eskom’s generation activities, funding and tariffs, independent power producers and prospects for the sector.
This Week's Magazine
As the City of Ekurhuleni continues its bid to develop the largely industrialised metropole into the continent’s first aerotropolis, executive mayor Mondli Gungubele has committed the city to creating a predictable, stable and enabling business environment in which...
While Ford Motor Company of Southern Africa (FMCSA) did not have “significant issues” with power supply in Gauteng, it was a different story in the Eastern Cape, said FMCSA and American Chamber of Commerce in South Africa president Jeff Nemeth earlier this month....
In 2000, exports into Africa from South Africa represented less than 5% of the turnover of Federal Mogul Motorparts Africa, with sales largely centred around Zimbabwe, Zambia, Malawi and Mozambique. Today, African exports represent 30% of sales, with trade expanded...
The Malawi government has launched a $50-million project to upgrade the Kamuzu barrage, on the Shire river, an outlet of Lake Malawi, which is used to control the flow of water from the lake to the lower Shire area. The project will run from this year to 2017 and...
Our new Technical and Vocational Education and Training (TVET) Colleges will replace the Further Education and Training (FET) Colleges which have served us for the past twenty years. The buildings will be the same and most of the staff will be the same but as the...